In this How-To, we'll cover the basics of creating a Constraint Profile and adding Physics Constraints to it.
Open or Create a Physics Asset for your Skeletal Mesh using the Content Browser.
If opting to create a new Physics Asset, you'll need to set it up before continuing.
Open the Physics Asset window by using the Window Menu -> Physics Asset option.
Add Profile using the + button on the Constraints Profile entry, and set its name (in the image below we've named it DocsConstraintProfile).
Close the Physics Assset Window.
Using the Profile Button, select the desired Constraint Profile to edit (again, we've chosen DocsConstraintProfile).
Switch the Physics Asset Editor to Constraints Mode using the Constraints button.
Select the Physics Constraints you wish to include in the Constraint Profile.
Press the Add to Current Profile button in the Details Panel.
Adjust the settings for the selected Physics Constraints.
Repeat steps 7-9 for Physics Constraints you desire to have in the Physical Animation Profile.
Save your Physics Asset using the Save button in the Physics Asset Tool.
The Physics Asset will have a profile that can be called upon from Blueprint or C++ to change its Physical Constraint properties.